Biostatistics – Wayne W. Daniel, Chad L. Cross – 10th Edition

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This 10th edition of Biostatistics: A Foundation for Analysis in the Health Sciences, 10th Edition should appeal to the same audience for which the first nine editions were written: advanced undergraduate students, beginning graduate students, and health professionals in need of a on methodology. Like its predecessors, this edition requires few mathematical prerequisites.

Only reasonable proficiency in algebra is required for an understanding of the concepts and underlying the calculations. The emphasis continues to be on an intuitive understanding of principles rather than an understanding based on mathematical sophistication. For most of the techniques covered in this edition, we discuss the capabilities of one or more packages (MINITAB, SAS, SPSS, and NCSS) that may be used to perform the calculations needed for their application. Resulting screen displays are also shown.

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  • CHAPTER 1: INTRODUCTION TO BIOSTATISTICS
    1.1 Introduction
    1.2 Some Basic Concepts
    1.3 Measurement and Measurement Scales
    1.4 Sampling and Statistical Inference
    1.5 The Scientific Method and the Design of Experiments
    1.6 Computers and Biostatistical Analysis
    1.7 Summary

    CHAPTER 2: DESCRIPTIVE STATISTICS
    2.1 Introduction
    2.2 The Ordered Array
    2.3 Grouped Data: The Frequency Distribution
    2.4 Descriptive Statistics: Measures of Central Tendency
    2.5 Descriptive Statistics: Measures of Dispersion
    2.6 Summary

    CHAPTER 3: SOME BASIC PROBABILITY CONCEPTS
    3.1 Introduction
    3.2 Two Views of Probability: Objective and Subjective
    3.3 Elementary Properties of Probability
    3.4 Calculating the Probability of an Event
    3.5 Bayes' Theorem, Screening Tests, Sensitivity, Specificity, and Predictive Value Positive and Negative

    CHAPTER 4: PROBABILITY DISTRIBUTIONS
    4.1 Introduction
    4.2 Probability Distribution of Discrete Variables
    4.3 The Binomial Distribution
    4.4 The Poisson Distribution
    4.5 Continuous Probability Distributions
    4.6 The Normal Distribution
    4.7 Normal Distribution Applications
    4.8 Summary

    CHAPTER 5: SOME IMPORTANT SAMPLING DISTRIBUTIONS
    5.1 Introduction
    5.2 Sampling Distributions
    5.3 Distribution of the Sample Mean
    5.4 Distribution of the Difference Between Two Sample Means
    5.5 Distribution of the Sample Proportion
    5.6 Distribution of the Difference Between Two Summary
    5.7 Summary

    CHAPTER 6: ESTIMATION
    6.1 Introduction
    6.2 Confidence Interval for a Population Mean
    6.3 The t Distribution
    6.4 Confidence Interval for the Difference Between Two Population Means
    6.5 Confidence Interval for a Population Proportion
    6.6 Confidence Interval for the Difference Between Two Population Proportions
    6.7 Determination of Sample Size for Estimating Means
    6.8 Determination of Sample Size for Estimating Proportions
    6.9 Confidence Interval for the Variance of a Normally Distributed Population
    6.10 Confidence Interval for the Ratio of the Variances of Two Normally Distributed Populations
    6.11 Summary

    CHAPTER 7: HYPOTHESIS TESTING
    7.1 Introduction
    7.2 Hypothesis Testing: A Single Population Mean
    7.3 Hypothesis Testing: The Difference Between Two Population Means
    7.4 Paired Comparisons
    7.5 Hypothesis Testing: A Single Population Proportion
    7.6 Hypothesis Testing: The Difference Between Two Population Proportions
    7.7 Hypothesis Testing: A Single Population Variance
    7.8 Hypothesis Testing: The Ratio of Two Population Variances
    7.9 The Type II Error and the Power of a Test
    7.10 Determining Sample Size to Control Type II Errors
    7.11 Summary

    CHAPTER 8: ANALYSIS OF VARIANCE
    8.1 Introduction
    8.2 The Completely Randomized Design
    8.3 The Randomized Complete Block Design
    8.4 The Repeated Measures Design
    8.5 The Factorial Experiment
    8.6 Summary

    CHAPTER 9: SIMPLE LINEAR REGRESSION AND CORRELATION
    9.1 Introduction
    9.2 The Regression Model
    9.3 The Sample Regression Equation
    9.4 Evaluating the Regression Equation
    9.5 Using the Regression Equation
    9.6 The Correlation Model
    9.7 The Correlation Coefficient
    9.8 Some Precautions
    9.9 Summary

    CHAPTER 10: MULTIPLE REGRESSION AND CORRELATION
    10.1 Introduction
    10.2 The Multiple Linear Regression Model
    10.3 Obtaining the Multiple Regression Equation
    10.4 Evaluating the Multiple Regression Equation
    10.5 Using the Multiple Regression Equation
    10.6 The Multiple Correlation Model
    10.7 Summary

    CHAPTER 11: REGRESSION ANALYSIS: SOME ADDITIONAL TECHNIQUES
    11.1 Introduction
    11.2 Qualitative Independent Variables
    11.3 Variable Selection Procedures
    11.4 Logistic Regression
    11.5 Summary

    CHAPTER 12: THE CHI-SQUARE DISTRIBUTION AND THE ANALYSIS OF FREQUENCIES
    12.1 Introduction
    12.2 The Mathematical Properties of the Chi-Square Distribution
    12.3 Tests of Goodness-of-Fit
    12.4 Tests of Independence
    12.5 Tests of Homogeneity
    12.6 The Fisher Exact Test
    12.7 Relative Risk, Odds Ratio, and the Mantel-Haenszel Statistics
    12.8 Summary

    CHAPTER 13: NONPARAMETRIC AND DISTRIBUTION-FREE STATISTICS
    13.1 Introduction
    13.2 Measurement Scales
    13.3 The Sign Test
    13.4 The Wilcoxon Signed-Rank Test for Location
    13.5 The Median Test
    13.6 The Mann-Whitney Test
    13.7 The Kolmogorov-Smirnov Goodness-of-Fit Test
    13.8 The Kruskal-Wallis One-Way Analysis of Variance by Ranks
    13.9 The Friedman Two-Way Analysis of Variance by Ranks
    13.10 The Spearman Rank Correlation Coefficient
    13.11 Nonparametric Regression Analysis
    13.12 Summary

    CHAPTER 14: SURVIVAL ANALYSIS
    14.1 Introduction
    14.2 Time-to-Event Data and Censoring
    14.3 The Kaplan-Meier Procedure
    14.4 Comparing Survival Curves
    14.5 Cox Regression: The Proportional Hazards Model
    14.6 Summary

    CHAPTER 15: VITAL STATISTICS (ONLINE)
    15.1 Introduction
    15.2 Death Rates and Ratios
    15.3 Measures of Fertility
    15.4 Measure of Morbidity
    15.5 Summary

    APPENDIX: STATISTICAL TABLES
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