Organic Chemistry – J. Clayden, N. Greeves, S. Warren, P. Wothers – 1st Edition


A first and second year undergraduate textbook, specifically geared to British and European courses and courses offered in better schools in North America. The emphasis is on clarity and understanding, with very careful explanations of difficult concepts, many examples related to everyday life, and a fresh and student-friendly style.

The book accompanies the beginner in from the structure of the molecules, over NMR up to the topics for advanced, like heterocycles and asymmetrical synthesis. A typical arrangement of functional groups as seen in older text does not occur. Thus, rather and concepts of with rising difficulties are explained. Therefore it can be seen , that a certain mechanism (e.g. the addition to a carbonyl group) can be applied to different functional groups.

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Table of Contents

1 What is organic chemistry?
2 Organic structures
3 Determining organic structures
4 Structure of molecules
5 Organic reactions
6 Nucleophilic addition to the carbonyl group
7 Delocalization and conjugation
8 Acidity, basicity, and pKa
9 Using organometallic reagents to make C-C bonds
10 Conjugate addition
11 Proton nuclear magnetic resonance
12 Nucleophilic substitution at the carbonyl (C=O) group
13 Equilibria, rates, and mechanisms: summary of mechanistic principles
14 Nucleophilic substitution at C=O with loss of carbonyl oxygen
15 Review of spectroscopic methods
16 Stereochemistry
17 Nucleophilic substitution at saturated carbon
18 Conformational analysis
19 Elimination reactions
20 Electrophilic addition to alkenes
21 Formation and reactions of enols and enolates
22 Electrophilic aromatic substitution
23 Electrophilic alkenes
24 Chemoselectivity: selective reactions and protection
25 Synthesis in action
26 Alkylation of enolates
27 Reactions of enolates with aldehydes and ketones: the aldol reaction
28 Acylation at carbon
29 Conjugate addition of enolates
30 Retrosynthetic analysis
31 Controlling the geometry of double bonds
32 Determination of stereochemistry by spectroscopic
33 Stereoselective reactions of cyclic compounds
34 Diastereoselectivity
35 Pericyclic reactions 1: cycloadditions
36 Pericyclic reactions 2: sigmatropic and electrocyclic reactions
37 Rearrangements
38 Fragmentation
39 Radical reactions
40 Synthesis and reactions of carbenes
41 Determining reaction mechanisms
42 Saturated heterocycles and stereoelectronics
43 Aromatic heterocycles 1: structures and reactions
44 Aromatic heterocycles 2: synthesis
45 Asymmetric synthesis
46 Organo-main-group chemistry I: sulfur
47 Organo-main-group chemistry II: boron, silicon, and tin
48 Organometallic chemistry
49 The chemistry of life
50 Mechanisms in biological chemistry
51 Natural products
52 Polymerization
53 Organic chemistry today

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